Arteries are similar to the plumbing that carries water to your home; if there is a substance clogging your plumbing then the flow of water is going to be reduced or shut off. Cholesterol plaques clog arteries and cause blood flow to be reduced or even completely blocked off. High cholesterol is thought to be a cause of heart disease, as high blood cholesterol is correlated to atherosclerosis, or a thickening of the artery walls due to plaque buildup. The artery walls are thickened due to the accumulation of cholesterol plaques that slowly block the flow of blood.


Coronary artery disease (CAD) is the result of advanced atherosclerosis in the arteries that supply blood to the heart itself. Once coronary artery disease has developed, plaques have built up substantially in the blood vessels of the heart and the arteries become narrowed. Arginine as a supplement can reduce the impact of coronary artery disease on the body. Arginine improves blood flow throughout the entire body and in the heart by increasing the body’s available nitric oxide levels.


Nitric oxide causes the endothelium, or the layer of cells lining the blood vessels of the body to relax and allow blood to flow with less resistance. Reduced endothelium function in the body results in hypertension, or high blood pressure, and this condition is often seen in people with a high cholesterol level or CAD. Arginine improves endothelium function for people with CAD and high cholesterol.


Arginine is scientifically proven to cause an increase in vasodilation, or the widening of the blood vessels of the body. Arginine was shown to reduce the amount of cholesterol related artery lesion in preliminary animal experiments, and arginine was also shown to improve exercise tolerance in patients that have developed coronary artery disease.


Angina or chest pain is a common very uncomfortable symptom reported in those with coronary artery disease, and a regular arginine supplement can reduce angina. Early diagnosis of coronary artery disease and treatment is important for successfully preventing a heart attack. A daily arginine supplement can improve the symptoms of coronary artery disease, and arginine can help to prevent the development of coronary artery disease along with a healthy diet and exercise.